Conjugation Scientist

Do you have a passion for Science? Would you like to apply your expertise to impact a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the one for you!

At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.

About AstraZeneca in Gaithersburg, MD:

Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world.  This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration.

The Gaithersburg site offers a variety of amenities to help boost productivity and help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center. This is where you’ll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams. 

Summary of the group: Members of the Purification Process Sciences group within Biopharmaceutical Development work closely with other groups in R&D, with Manufacturing Sciences, and Global Technical Operations to develop and transfer clinical and commercial purification and conjugation processes.

Main Duties & Responsibilities

• This position is a laboratory-based role, the main responsibility will be the development of conjugation and purification processes for antibody-drug conjugates (ADCs).
  • Design, execute, analyze conjugation studies and purification studies to develop and optimize processes for the manufacturing of antibody-drug conjugates (ADCs)
  • Support process scale-up and tech transfer activities to manufacturing sites
  • Author reports and contribute to regulatory documents
  • Develop and evaluate novel technologies
  • Collaborate with cross-functional groups in Research and Development in order to meet project timelines and company goals
  • Present results at internal meetings

Education & Experience Requirements:

Education

BS or MS degree in Bioengineering, Biochemistry, or related field.

Experience: BS and 5+ yrs experience OR MS and 2+ yrs experience

Required Skills

• Experience working with proteins, protein purification, including chromatography, filtration, tangential flow filtration
• Experience operating LC/HPLC systems such as AKTA Avant and Agilent HPLC
• Good understanding of protein biochemistry, protein characterization, and analytical techniques
• High critical thinking skills and attention to detail
• Ability to work effectively as a member of cross-functional teams
• Very good oral and written communication skills

Desired Skills

• Experience with protein conjugation
• Experience with statistical design of experiments

Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognising their potential. Join us on our journey of building a new kind of organisation to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey.

So, what’s next!

Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available and we hope it’s yours.

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.