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Waltham, Massachusetts, United States
Job reference: R-046285
Posted date: May. 31, 2019

AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialisation of prescription medicines for some of the world’s most serious diseases. We're proud to have a unique workplace culture that inspires innovation and collaboration. We believe in the potential of our people and you’ll develop beyond what you thought possible.

The new R&D Oncology organisation brings together early and late oncology teams, from discovery through to late-stage development, with oncology specific Regulatory and Biometrics groups.

You’ll be in a global pharmaceutical environment but also exposed to strong rigorous academic science. For example, every postdoc has an external academic mentor to ensure we are working and publishing at the highest level in a field. What’s more, you’ll have the support of a leading academic advisor, who’ll provide you with the guidance and knowledge you need to develop your career.

You’ll be associated with a project aligned with our scientific platform of Tumour Driver and Resistance, aiming to elucidate the mechanism of an epigenetic protein that functions as a resistance mechanism for cancer and define the combination strategy to overcome the drug resistance.

Education and Experience required:


  • PhD in oncology, cell biology, or related field
  • Strong desire to learn and perform cancer research in an industry setting
  • Expertise in epigenetic oncology and/or RTK signalling pathways
  • Strong scientific background in mechanisms of disease and drug resistance.
  • Experience with a variety of laboratory, molecular, and cellular biology techniques  


  • Relevant bioinformatic experience

Skills and Capabilities required:

  • Highly motivated, innovative and reliable with the ability to effectively problem solve
  • Flexible, collaborative and team-oriented mind set
  • Strong publication track record
  • Excellent communication skills (oral and written)

This is a 3-year programme.  2 years will be a Fixed Term Contract, with a 1-year extension which will be merit based.  The role will be based in Waltham, MA, USA, with a competitive salary on offer. To apply for this position, please click the apply link below.

Advert opening date – 31st May 2019 / Advert closing date – 9th August 2019

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law.

Postdoc Fellow - Epigenetic modifier and drug resistance

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