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San Francisco, California, United States
South San Francisco, California, United States
Job reference: R-047418
Posted date: Mar. 21, 2019

If you’re inspired by the possibilities of science to change lives and you thrive when making brave decisions – join us.

MedImmune is the worldwide biologics research and development arm of AstraZeneca. Here, you’ll have the opportunity to make a difference in people’s lives every day. As one of the world’s premier biotechnology companies, our mission is centered on delivering life-changing products that advance world health, and help fight and cure disease.  Here at MedImmune, you’ll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients’ lives.

We’re constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it. We’re pioneering innovative research and exploring novel pathways across key therapeutic areas including oncology, respiratory, inflammation and autoimmunity, cardiovascular and metabolic disease, and infection and vaccines. And we’re industry-leading in immunology, protein engineering and translational science. We offer a unique and strong collaborative network as part of the AstraZeneca family, as together we explore synergies between small and large molecules.

MedImmune has a dynamic environment that fosters collaboration and innovation. We attract top minds, and we nurture and build top talent.

Position Summary:  

This position provides support for biotherapeutic projects, including but are not limited to development, validation, and conduct of immunoassays for determination of drug relevant biomarkers in biological matrices. Familiarity with GLP regulations is a plus.

Major Duties and Responsibilities:

• Execute assay development, qualification and validation and sample testing of different types of phenotypic and functional assays in a timely manner

• Develop immunochemical and cell-based assays for measurement of potential pharmacodynamic markers and for measurement of neutralizing anti-drug antibodies in in biological matrices such as whole blood, serum and/or plasma

• Conduct bio-analytical sample analysis in support of Non-GLP pharmacology in vivo studies

• Prepare Standard Operating Procedures, validation protocols and reports and contribute to technical reports

• Maintain lab routines to ensure lab safety and instrument compliance

• Communicate effectively with vendors and contract labs


For Associate Scientist II - Bachelor's Degree in a scientific discipline and 8-10 years of relevant experience, or Master's Degree in a scientific discipline and 5-8 years of relevant experience;

For Scientist I - Bachelor's Degree in a scientific discipline and 10-13 years of relevant experience, or Master's Degree in a scientific discipline and 8-10 years of relevant experience, or PhD in a scientific discipline and 0-3 years of relevant experience

• Strong background in immunoassay and cell-based assay development, including experience with ELISA, MSD and other platforms

• Experience working with biological matrices such as whole blood, serum and plasma a plus

• Knowledge of assay validation guidelines and GLP regulations a plus

• Proficiency with spreadsheet, word processing, and graphical computer programs (MS EXCEL, MS WORD, Graphpad Prism, for example) required

Candidates should have prior experience working successfully in a matrix environment, multi-tasking and prioritizing work, designing experience and interpreting data.

Next Steps – Apply today!

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity.  If you know someone who would be a great fit, please share this posting with them.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law

Scientist I or Associate Scientist II - Immunoassay Development

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