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Gothenburg, Västra Götaland County, Sweden
Cambridge, England, United Kingdom
Job reference: R-039432
Posted date: Feb. 15, 2019

Senior and Principal Modelling & Simulation Specialists, Quantitative Solutions

Location- Cambridge (UK) or Gothenburg (Sweden)

At AstraZeneca we are excited by the possibilities of what science can do. When we deliver a life-changing medicine, that success comes from the combined efforts of all of our people.

Our Advanced Analytics Centre (AAC) uses a blend of scientific and technical skills (statistics, informatics, computer science, mathematics and tool development) to develop and deliver cutting-edge methods which address critical scientific and business questions in drug development.

Quantitative Solutions (QS) is a centre of excellence within the AAC for high quality delivery of advanced analytics services, tasks and tools.

We are seeking Modelling and Simulation Specialists at both Senior and Principal level to join our team of like minded colleagues, solving challenging technical problems.


Within this role, you can look forward to ground-breaking work and the opportunity to add value in a broad range of activities.

As a Senior / Principal Modelling & Simulation Specialist you will be part of the Quantitative Solutions team providing advanced solutions in support of the drug development portfolio, for example:

  • Trial design simulations
  • Network meta-analyses
  • Data visualisations
  • Ad-hoc clinical trial data analysis
  • Technical expertise on tool development to staff within QS, AAC & AstraZeneca

You will be responsible for providing technical expertise and consultancy for projects in the AAC on modelling & simulation, providing the business with a range of innovative solutions to a variety of technical questions in drug development.

You’ll join a truly global team that pulls together to put patients first. Working with some of the most respected statistical programming, statistics, information practice and advanced analytics experts in the industry. As part of a small development team you will be responsible for planning, building & maintaining robust, repeatable solutions and contributing to the development of new software tools, for frequently occurring analyses.  This will include determining project scope, documenting requirements and ensuring the quality of tools provided.

Main Duties and Responsibilities

You will provide technical consultancy on a wide range of statistical analyses, including modelling & simulation, on an individual basis or with a team of statisticians working in the same field.

Working alongside others, you will contribute to the development of new software tools, including stakeholder interactions, requirements analysis, proof of concept, user acceptance testing and project management; ensuring that our tools are developed and validated to AstraZeneca and regulatory standards.

You will take responsibility for selected tools initiated within the AAC, using them to provide solutions to questions from ongoing clinical trials.  You will also be responsible for improving the productivity, scalability and ease of use of existing tools and solutions.

You will demonstrate a high standard of attention to quality, including best practice record keeping, project management, documentation and adherence to standards.

At Principal level you will take greater ownership of projects, and also inspire and mentor more junior colleagues within the Quantitative Solutions group.


We are seeking collaborative colleagues who enjoy technically challenging work. You’ll be a confident communicator who can share your ideas and engage with stakeholders.


  • MSc or PhD in bio statistics, mathematics, informatics or related subject
  • Experience of modelling, simulation and statistical computing, primarily R
  • Broad understanding of clinical drug development & the pharmaceutical environment


  • Experience, or understanding, of end-to-end software tool/solution development and life cycle management

This role could be offered at either Senior or Principal level, depending on your experience.

Salary - Competitive salary and company benefits apply

To be considered for this exciting opportunity, please apply today.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, gender or gender orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law.

Closing date for applications – 29th March 2019

Senior and Principal Modelling & Simulation Specialists
Clinical Development

AstraZeneca in the UK

Our 6,700-strong UK workforce is based across seven sites in the UK, including our new research facilities and global corporate headquarters in Cambridge. The Cambridge Biomedical Campus (CBC) is globally renowned as a leading centre of research, education and patient care. For AstraZeneca, the campus is the perfect environment in which to foster a vibrant culture of open innovation and collaboration.

Learn more

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