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Gaithersburg, Maryland, United States
Job reference: R-046441
Posted date: Mar. 07, 2019

If you’re inspired by the possibilities of science to change lives and you thrive when making brave decisions – join us.

MedImmuneis the worldwide biologics research and development arm of AstraZeneca. Here, you’ll have the opportunity to make a difference in people’s lives every day. As one of the world’s premier biotechnology companies, our mission is centered on delivering life-changing products that advance world health, and help fight and cure disease.  As aPostdoctoral Fellow - ProteomicsinGaithersburg, MDyou’ll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients’ lives.

We’re constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it. We’re pioneering innovative research and exploring novel pathways across key therapeutic areas including oncology, respiratory, inflammation and autoimmunity, cardiovascular and metabolic disease, and infection and vaccines. And we’re industry-leading in immunology, protein engineering and translational science. We offer a unique and strong collaborative network as part of the AstraZeneca family, as together we explore synergies between small and large molecules.

MedImmune has a dynamic environment that fosters collaboration and innovation. We attract top minds, and we nurture and build top talent.

This post-doctoral fellowship in Proteomics provides a unique opportunity to work with a team of experienced mass spectrometrists engaged in proteomics, mAb characterization and metabolomics. The goal is to conduct cutting-edge research to unravel key targets in drug discovery, understanding the targets in complex disease conditions using state-of-the-art tandem mass spectrometry approach to facilitate R&D scientists from ADPE, therapeutic areas from Oncology, Cardiovascular Renal Metabolism and Respiratory Diseases. In-depth knowledge of proteomics technology, data analysis skills and biological interpretation of data is necessary to successfully carry out the functions of this position.

Essential requirements:

  • A Ph.D. in biochemistry, chemistry, analytical chemistry or any related life science field with a focus on mass spectrometry.
  • Hands-on experience in carrying out protein digestion, peptide purification and mass spectrometry data analysis.
  • Current knowledge of proteomics technology including nanoflow LC-MS analysis, proteomics data analysis software, protein and peptide quantitation.
  • Knowledge of ideal mass spectrometry sample preparation from complex samples derived from various biological sources including cells, tissues, and body fluids.
  • Experience in operating and troubleshooting mass spectrometry instruments.
  • Excellent scientific writing, presentation and communication skills.

Desirable Requirements

  • Experience in analysis of a wide variety of post-translational modifications.
  • Ability to independently carry out validation experiments in cell culture models.
  • Understanding of statistical tools and basic knowledge of bioinformatics analysis of the data using pathway analysis tools such as GO, IPA, KEGG and Cytoscape.
  • Motivation to develop new tools for MS analysis and MS data analysis and constantly update with the current knowledge in the Omics field.
  • Publications in high impact journals and scientific talks in conferences.

Next Steps – Apply today!

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity. If you know someone who would be a great fit, please share this posting with them.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law.

Postdoctoral Fellow - Proteomics

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