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Gaithersburg, Maryland, United States
Job reference: R-046444
Posted date: Mar. 07, 2019

If you’re inspired by the possibilities of science to change lives and you thrive when making brave decisions – join us.

MedImmuneis the worldwide biologics research and development arm of AstraZeneca. Here, you’ll have the opportunity to make a difference in people’s lives every day. As one of the world’s premier biotechnology companies, our mission is centered on delivering life-changing products that advance world health, and help fight and cure disease.  As aPostdoctoral Fellow - ProteomicsinGaithersburg, MDyou’ll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients’ lives.

We’re constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it. We’re pioneering innovative research and exploring novel pathways across key therapeutic areas including oncology, respiratory, inflammation and autoimmunity, cardiovascular and metabolic disease, and infection and vaccines. And we’re industry-leading in immunology, protein engineering and translational science. We offer a unique and strong collaborative network as part of the AstraZeneca family, as together we explore synergies between small and large molecules.

MedImmune has a dynamic environment that fosters collaboration and innovation. We attract top minds, and we nurture and build top talent.

Main Duties and Responsibilities

We are seeking a skilled and innovative Postdoctoral Fellow with extensive mass spectrometry (MS) experience. In this predominantly lab-based role, the successful candidate will be involved in the establishment of novel MS-based methods at the beginning of the drug development process. The candidate will explore both proteomics and metabolomics and contribute to ongoing efforts in the lab to expand omics capabilities. The position requires the ability to embrace new technologies and methods quickly as well as perform in a fast-paced, highly collaborative work environment. The candidate will have general knowledge of the fields of chemistry, biology, mass spectrometry, proteomics, and metabolomics. The analytical instruments in the lab include: Agilent 6560 IM-QTOF, Sciex QTRAP 6500, Thermo Orbitrap Fusion, Thermo Orbitrap ID-X, Thermo Q Exactive HF-X coupled to micro- and nano-ESI along with an EVOSEP One platform and 908 Devices ZipChip platform.


PhD (in Chemistry, Analytical Chemistry, Biochemistry, or related discipline)

Essential Requirements

  • Significant hands-on experience with mass spectrometry instrumentation.
  • Hands-on experience in at least ONE area of MS-based omics such as proteomics, peptidomics, metabolomics, or lipidomics.
  • Familiar with separation techniques such as liquid chromatography (LC) and/or capillary electrophoresis (CE).
  • Experience in preparation and analysis of biological matrices.
  • Ability to work outside established field of expertise.
  • Proven ability to work well collaboratively in a team environment; report results internally to fellow researchers through weekly meetings and externally through conference presentations and peer-reviewed publications.

Desirable Requirements

  • Experience with any of the mass spectrometers listed above.
  • General familiarity with MS data analysis software and bioinformatics tools for metabolomics and/or proteomics studies.
  • Experience with protein/peptide/metabolite quantitation methods.
  • Experience with automation/liquid handler platforms.
  • Demonstrate strong written, verbal, and interpersonal communication skills.
  • Willingness and flexibility to operate in a fast-paced environment and adapt to changing deadlines/priorities.

Next Steps – Apply today!

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity. If you know someone who would be a great fit, please share this posting with them.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law.

Postdoctoral Fellow - Proteomics/Metabolomics

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