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Cambridge, England, United Kingdom
Waltham, Massachusetts, United States
Job reference: R-033331
Posted date: Feb. 06, 2019

Position:          Associate Director/Director Physician

Locations:         Waltham MA or Cambridge, UK

At AstraZeneca, we work together across global boundaries to discover, develop, manufacture and market prescription medicines that make a positive impact on the lives of patients as well as their families and communities.  At AstraZeneca, our vision is redefining cancer, redefining our solutions to cancer and restoring patients' lives.  Our mission is to make a meaningful difference to patient health through great medicines that bring benefit for patients and add value for society.

Early Clinical Development is the place where science meets the patient.  We work closely with our colleagues in Bioscience, Discovery Sciences, Drug Safety and Metabolism, Pharmaceutical Sciences and Personalised Healthcare and Biomarkers amongst others, on drug target identification, lead optimization and candidate drug selection, and across the early phases of small molecule clinical drug development in oncology through to the end of Phase 2 and determination of proof of concept.

By building a diversity of expertise and experience in the oncology Translational Medicine Unit, it is our intention to create a global centre of excellence at AstraZeneca in pharma training for oncologists joining the industry.

Your responsibilities as the Associate Director/Director Physician:

  • Be the senior clinical resource within your allocated cross-functional innovative medicines project teams of experienced drug developers.

  • Be integral to the design, conduct, monitoring, data interpretation, reporting and publication of all clinical studies across the early clinical development portfolio for that project or projects.

  • Develop and mentor more junior clinicians within the unit.

  • Serve as the accountable medical leader for a specific early development project or projects.

  • Be agile, pioneering and collaborative in your position as the key medical contact for allocated projects, ensuring the ethical and scientific integrity of all activities, and in compliance with Good Clinical Practice and all relevant regulatory requirements.

  • Create personal networks within AstraZeneca, and draw upon our world-class, specialist early oncology development community to ensure peer-reviewed and collaborative clinical input into translational science, personalised healthcare and biomarker, quantitative clinical pharmacology, bioinformatics and other development-related strategies to assure the very highest standards of quality, and scientific and clinical validity.

  • Be actively internally and externally facing, including both high-level and detailed interactions with regulatory agencies, ethics committees, clinical investigators, site staff and study monitors, disease area thought leaders, CRO employees and the wide community of other professionals involved in the clinical development process.

  • Maintain a high degree of awareness of new and emerging medical developments, and rapidly and accurately integrate and effectively communicate all sources of data, internal and external, relevant to your project(s) to inform our ongoing research and development.


  • An MD degree or equivalent from a recognized school of medicine.
  • Specialty training or board eligibility in medical oncology (or a closely allied field).
  • Either pharmaceutical industry experience, and/or significant experience in clinical oncology practice, and a proven track record in clinical oncology research and publication.
  • A track record of being responsive to scientific data, with an ability to demonstrate how you have followed and adapted to emerging science and innovation in your research.
  • A collaborative outlook with a natural ability to work in teams and across functions in an environment of peers, along with a flexible and entrepreneurial spirit and a real willingness to roll up your sleeves.
  • Strong written and spoken English skills, with the ability to present, write and review technical clinical documents and reports.
  • Ability to travel nationally and internationally.

Desirable skills and attributes include:

  • An oncology-focused PhD.
  • Prior work experience within the pharmaceutical industry, or of working with it.
  • Work experience across multiple organizations and geographies.

Next Steps – Apply today!

  • AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines for some of the world’s most serious diseases. But we're more than one of the world's leading pharmaceutical companies. At AstraZeneca, we're proud to have a unique workplace culture that inspires innovation and collaboration. Here, employees are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.

  • To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity.  If you know someone who would be a great fit, please share this posting with them.

AstraZeneca is an equal opportunity employer.  AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.

Associate Director/Director Physician
Clinical Development

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